Thyroid disease

Multiple overlapping microwave ablation in benign thyroid nodule: a single-center 24-month study

Eur Thyroid JPublished Prospective cohort study

Authors' conclusion

The novel microwave ablation system presented herein can help achieve good clinical success rate in benign thyroid nodules with a satisfying safety profile. The microwave ablation performed with the multiple overlapping ablation technique could be a good alternative to surgery and radiofrequency ablation in the management of benign thyroid nodules.

Study context

Population
Benign symptomatic thyroid nodules
Participants
30 nodules
Outcome
Volume reduction rate
Follow-up
Months 1, 3, 6, 9, 12 and 24
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Volume reduction rate, month 1
32%
Volume reduction rate, month 3
59%
Volume reduction rate, month 6
67%
Volume reduction rate, month 9
69%
Volume reduction rate, month 12
73%
Volume reduction rate, month 24
81%

Observational data: associations, not effects.

Further findings

Symptom and cosmetic scores · before vs after treatment

Mean symptom score before treatment
4
Mean symptom score after treatment
3
Mean cosmetic score before treatment
3
Mean cosmetic score after treatment
1

Thyroid function

Thyroid function indicators fluctuated in the normal range; those with hyperthyroidism recovered to normal

Safety

Complications · procedure to 30 days postoperatively

Temporary laryngeal paralysis, fully recovered in <3 months
1 case

Original publication

Multiple overlapping microwave ablation in benign thyroid nodule: a single-center 24-month study. Eur Thyroid J. Published 25 January 2023. doi:10.1530/etj-22-0175

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