Osteoporosis, bone & mineral

Moderate alcohol consumption is associated with higher risk of distal radius fracture in middle-aged adults: a case-control study

Osteoporos IntPublished case-control study

Main finding · Distal radius fracture, participants aged 40-59 yearsResult — go to the resultOdds ratio 1.98 95% CI 1.04–3.78

Authors' conclusion

Moderate alcohol consumption was associated with increased odds of distal radius fracture among individuals aged 40-59 years. These findings suggest that alcohol consumption below current high-risk thresholds may also be relevant when assessing fracture risk.

Study context

Population
Patients with a distal radius fracture and controlspatients with a distal radius fracture 288 · controls 197
Comparison
Fracture risk was compared between participants reporting moderate alcohol consumption (1-3 times/week) and those reporting less than weekly consumption
Outcome
Distal radius fracture, participants aged 40-59 years

Main finding

As reported in the abstract

Odds ratio

1.98

95% CI 1.04–3.78

P = 0.038

Moderate alcohol consumptionvs Less than weekly consumption
OR 1.98 (95% CI 1.04–3.78); P = 0.038

Observational data: associations, not effects.

Further findings

Fracture risk, participants ≥60 years

No difference in fracture risk was observed among participants ≥60 years

Baseline characteristics

Mean age among fracture patients
62.9 years (SD 10.3)
Mean age among controls
60.4 years (SD 10.5)
Women among fracture patients
80.6%
Women among controls
82.8%
Among fracture patients, abstainers were older and more often used ≥3 medications

Original publication

Moderate alcohol consumption is associated with higher risk of distal radius fracture in middle-aged adults: a case-control study. Osteoporos Int. Published 14 November 2026. doi:10.1007/s00198-026-08326-6

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