Mitigating Severe Hypoglycemia in Users of Advanced Diabetes Technologies: Impaired Awareness of Hypoglycemia and Unhelpful Hypoglycemia Beliefs as Targets for Interventions
Authors' conclusion
Psychoeducation (BGAT and HARPdoc) was effective in reducing SH in people using ADTs. HARPdoc may also provide greater long-term SH reduction and improves psychological well-being in this patient group.
Study context
- Population
- People with T1D and problematic hypoglycemia persisting despite optimized care, using advanced diabetes technologies (CGM or AID)
- Participants
- 45 ADT users
- Comparison
- HARPdoc vs Blood Glucose Awareness Training (BGAT)
- Primary endpoint
- Severe hypoglycemia (SH) incidence
Methodological detailssubgroup analysis
- Subgroup analysis
Primary result
As reported in the abstract
SH incidence
- BGAT and HARPdoc both reduced severe hypoglycemia (SH) incidence by more than 50%
- P < 0.0001
Further findings
Hypoglycemia awareness (Gold questionnaire)
- Both interventions improved hypoglycemia awareness
- P < 0.05
Unhelpful hypoglycemia beliefs (A2A), diabetes distress (Problem Areas in Diabetes (PAID)), anxiety (Hospital Anxiety and Depress Scale (HADS)-anxiety)
- HARPdoc mitigated unhelpful hypoglycemia beliefs
- P < 0.0001
- HARPdoc mitigated diabetes distress
- P < 0.05
- HARPdoc mitigated anxiety symptoms
- P < 0.05
- BGAT demonstrated no significant impacts in these respects
Depression symptoms (HADS-depression)
- Neither HARPdoc nor BGAT had significant effects on depression symptoms
Original publication
Mitigating Severe Hypoglycemia in Users of Advanced Diabetes Technologies: Impaired Awareness of Hypoglycemia and Unhelpful Hypoglycemia Beliefs as Targets for Interventions. Diabetes Technol Ther. Published 29 April 2024. doi:10.
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