Type 1 diabetes

HIT4HYPOS Continuous Glucose Monitoring Data Analysis: The Effects of High-Intensity Interval Training on Hypoglycemia in People With Type 1 Diabetes and Impaired Awareness of Hypoglycemia

J Diabetes Sci TechnolPublished Post hoc analysis of the HIT4HYPOS parallel-group study

Authors' conclusion

Based on CGM data collected from a real-world study of four weeks of HIIT versus no exercise in individuals with T1D and IAH, we conclude that HIIT does not increase hypoglycemia, and in fact reduces exposure to nocturnal hypoglycemia.

Study context

Population
People with T1D and impaired awareness of hypoglycemia (IAH)
Participants
18 people
Comparison
High-intensity interval training (HIIT) + continuous glucose monitoring (CGM) vs no exercise + CGM
Primary endpoint
Hypoglycemia frequency and duration (CGM)
Follow-up
Four weeks
Methodological details4 weeks of CGM data
  • 4 weeks of CGM data

Primary result

As reported in the abstract

Total time in hypoglycemia, level 1 (THypo(L1))

P = 0.335

Further findings

Total time in hypoglycemia, level 2 (THypo(L2)) · four weeks

P = 0.146

Nocturnal hypoglycemia, level 1 (THypo(L1)) · four weeks

P = 0.076

Nocturnal hypoglycemia, level 2 (THypo(L2)) · four weeks · reduction in nocturnal hypoglycemia with HIIT

P = 0.006

Hypoglycemia event rate (EventPerWeekHypo) · four weeks

P = 0.340

Hypoglycemia duration (DurationHypo) · four weeks

P = 0.219

Original publication

HIT4HYPOS Continuous Glucose Monitoring Data Analysis: The Effects of High-Intensity Interval Training on Hypoglycemia in People With Type 1 Diabetes and Impaired Awareness of Hypoglycemia. J Diabetes Sci Technol. Published 23 September 2024. doi:10.1177/19322968241273845

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