Family History of Diabetes and Clinical Characteristics in Children at Diagnosis of Type 1 Diabetes—A Swedish Population-Based Study
Main finding · Parental T2DResult — go to the resultRelative risk 1.88Authors' conclusion
A family history of T2D and being overweight may contribute to increased risk of T1D.
Study context
- Population
- Swedish children at diagnosis of T1D; family history of diabetes in parents and grandparentschildren with T1D
- Participants
- 3,603 children
- Exposure
- Children with T1D vs general population cohort (parental diabetes); children with T1D with vs without family history of diabetes (clinical characteristics)
- T1Dn = 3,603
- Outcome
- Prevalence of parental diabetes in children with vs without T1D
Main finding
Parental T2D
Relative risk
1.88
P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Overweight or obesity at T1D diagnosis, by family history of T2DFamily history of T2D vs No family history of T2D · more likely with family history of T2D | P = 0.002 |
Original publication
Family History of Diabetes and Clinical Characteristics in Children at Diagnosis of Type 1 Diabetes—A Swedish Population-Based Study. Diabetes Care. Published 20 September 2024. doi:10.
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