Metformin use associated with lower rate of hospitalization for influenza in individuals with diabetes
Authors' conclusion
In patients with diabetes, metformin use is associated with lower rate of hospitalization following an emergency department visit for influenza.
Study context
- Population
- Adults with DM seen in any Duke University Medical Center-affiliated ED for influenza over a 6-year period; 59.9% female, mean age 62.9 years, 58.4% African American, 36.1% White, 81.9% obese or overweight
- Participants
- 1,023 adults
- Exposure
- Metformin use vs no metformin
- Metforminn = 347
- Outcome
- Hospital admission rate
Methodological detailsretrospective chart review, univariable and multivariable analyses
- Retrospective chart review
- Univariable and multivariable analyses
Main finding
As reported in the abstract
Hospitalization after ED visit for influenza
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
In-hospital LOS and in-hospital death (among those admitted)
- No statistically significant difference in LOS or death
Original publication
Metformin use associated with lower rate of hospitalization for influenza in individuals with diabetes. Diabetes Obes Metab. Published 14 May 2024. doi:10.
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