Lipids & metabolic liver disease
Metabolic Dysfunction‐Associated Steatotic Liver Disease in an Urban Paediatric Cohort With High Socioeconomic Deprivation
Authors' conclusion
Within a cohort of predominantly Hispanic children with MASLD and high socioeconomic disadvantage, there are significant laboratory and histologic differences in patients with higher SDI scores, suggesting increased MASLD severity.
Study context
- Population
- Urban children ≤18 years with suspected MASLD who underwent liver biopsy, January 2009–December 2019; predominantly Hispanic males with obesity, median age 12 years
- Participants
- 277 children
- Exposure
- High social deprivation index (SDI) vs lower SDI
- Outcome
- MASLD severity by SDI
Methodological detailsbiopsy-confirmed
- Biopsy-confirmed
Main finding
As reported in the abstract
Median SDI score
85
65–93
Observational data: associations, not effects.
Further findings
MASH vs MASLD
Median ALT, MASH vs MASLD
P < 0.001
Fibrosis vs No fibrosis
Median ALT, fibrosis vs no fibrosis
P < 0.001
Original publication
Metabolic Dysfunction‐Associated Steatotic Liver Disease in an Urban Paediatric Cohort With High Socioeconomic Deprivation. Pediatr Obes. Published 5 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →