Association of Niacin Intake, Obesity and Metabolic Dysfunction‐Associated Steatotic Liver Disease in Paediatric Patients: National Health and Nutrition Examination Survey
Main findingResult — go to the resultOdds ratio 0.55 95% CI 0.35–0.86Authors' conclusion
Adolescents with MASLD demonstrated distinct demographic, metabolic and biochemical profiles, particularly higher rates among Hispanic youth and an association with lower niacin intake.
Study context
- Population
- Participants aged 12–19 years, National Health and Nutrition Examination Survey (NHANES) 2017–2020, United States; those lacking niacin or anthropometric data excluded
- Exposure
- Niacin intake: highest quartile vs lowest quartile; MASLD vs no MASLD
- Outcome
- Association between dietary niacin intake (mean of two 24-h recalls) and MASLD
Main finding
As reported in the abstract
Odds ratio
0.55
95% CI 0.35–0.86
By group
Q4 niacin intakevs Q1 niacin intake
OR 0.55 (95% CI 0.35–0.86)
Observational data: associations, not effects.
Further findings
| Outcome | OR | P value |
|---|---|---|
| Hispanic ethnicity as independent risk factor for MASLD | 2.35 | P < 0.001 |
Clinical and biochemical profile, MASLD vs no MASLD
- Higher BMI measures, diastolic blood pressure, liver enzymes and glucose metabolism markers with MASLD (all p < 0.001)
- Elevated TG and LDL, reduced HDL with MASLD (all p < 0.001)
Original publication
Association of Niacin Intake, Obesity and Metabolic Dysfunction‐Associated Steatotic Liver Disease in Paediatric Patients: National Health and Nutrition Examination Survey. Pediatr Obes. Published 19 June 2026. doi:10.
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