Mediators and moderators of successful population-level weight management in primary care: results from the PATHWEIGH cluster-randomized pragmatic trial
Authors' conclusion
Altogether, the intervention had favorable effects on patient weight across the subgroups, particularly when a patient or provider used ≥1 EHR component of PATHWEIGH.
Study context
- Population
- Primary care patients, 56 primary care clinics in Colorado, USA
- Participants
- 274,182 patients56 clinics
- Comparison
- PATHWEIGH intervention vs usual care
- Primary endpoint
- Mediators and moderators associated with successful population-level weight management
Methodological detailsstepped-wedge, cluster-randomized, one-way crossover from usual care to intervention
- Stepped-wedge
- Cluster-randomized
- One-way crossover from usual care to intervention
Primary result
As reported in the abstract
18 months
- Proportion of additional patient weight loss mediated by patient and/or provider use of an electronic health record (EHR) component
- 37%
- Proportion of additional patient weight loss mediated by anti-obesity medication use
- 4%
- P for all comparisons
- p < 0.001
Original publication
Mediators and moderators of successful population-level weight management in primary care: results from the PATHWEIGH cluster-randomized pragmatic trial. Int J Obes (Lond). Published 2 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →