Obesity

Assessing Clinician Engagement With a Passive Clinical Decision Support System for Liver Fibrosis Risk Stratification in a Weight Management Clinic

Endocr PractPublished Mixed-methods implementation study

Authors' conclusion

This implementation strategy bundle did not achieve meaningful metabolic dysfunction-associated steatotic liver disease fibrosis risk stratification. Electronic health record-based CDSS shows promise but requires alignment with provider priorities, seamless workflow integration, and robust technical infrastructure.

Study context

Population
Weight management clinic visits; patients with elevated FIB-4
Comparison
Pre- vs postactivation of a 3-strategy implementation bundle
Outcome
Penetration: proportion of patients with elevated FIB-4 completing VCTE or hepatology referral
Methodological detailspre–post comparison, semi-structured provider interviews (i-PARIHS framework)
  • Pre–post comparison
  • Semi-structured provider interviews (i-PARIHS framework)

Main finding

As reported in the abstract

Penetration: patients with elevated FIB-4 completing VCTE or hepatology referral
  • Preactivation: no vibration-controlled transient elastography (VCTE) and 2 hepatology referrals (128 elevated FIB-4 scores)
  • Postactivation: 3 VCTE referrals and 2 hepatology referrals (234 elevated FIB-4 scores)
  • Postactivation vs Preactivation: Fischer's exact test P value = 1.00

Further findings

Visits with automated FIB-4 scores

Visits Preactivation 3933 · Postactivation 4634

Elevated scores Preactivation 128 · Postactivation 234

Provider interviews (acceptability and feasibility) · 3 months postimplementation

Barriers: shared responsibility with primary care, low awareness and trust in risk-stratification tools, workflow challenges, competing demands
Educational outreach and facilitation improved clinical decision support system (CDSS) engagement; technical issues reduced it

Original publication

Assessing Clinician Engagement With a Passive Clinical Decision Support System for Liver Fibrosis Risk Stratification in a Weight Management Clinic. Endocr Pract. Published 25 April 2025. doi:10.1016/j.eprac.2025.04.014

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