Low-carbohydrate diet in children and young people with type 1 diabetes: A randomized controlled trial with cross-over design
Authors' conclusion
Short-term LCD led to an improvement of glycemic parameters without increasing time in hypoglycemia, disturbing the lipid profile or negatively affecting the quality of life of CYPwD.
Study context
- Population
- Children and young people with T1D (20 female; 20 CSII; age 14.5 ± 2.9 years; HbA1c 48.9 ± 9.4 mmol/mol)cross-over
- Participants
- 35 children
- Comparison
- Low-carbohydrate diet vs recommended carbohydrate diet
- Primary endpoint
- Time in range (CGM)
Methodological detailscross-over
- Cross-over
Primary result
As reported in the abstract
TIR
P = 0.008
Further findings
Time in hyperglycaemia and average glycaemia
- Significantly lower with low-carbohydrate diet (LCD)
Glycaemic variability
- No difference between the diets
Body weight and BMI
- Significantly lower during LCD
Quality of life (QoL)
- No significant differences in self-assessed QoL
Safety
Time in hypoglycaemia
- No difference between the diets
LDL-C
- No significant difference
Original publication
Low-carbohydrate diet in children and young people with type 1 diabetes: A randomized controlled trial with cross-over design. Diabetes Res Clin Pract. Published 3 September 2024. doi:10. 1016/ j. diabres. 2024. 111844
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