Type 1 diabetes

Low-carbohydrate diet in children and young people with type 1 diabetes: A randomized controlled trial with cross-over design

Diabetes Res Clin PractPublished Randomised controlled trial

Authors' conclusion

Short-term LCD led to an improvement of glycemic parameters without increasing time in hypoglycemia, disturbing the lipid profile or negatively affecting the quality of life of CYPwD.

Study context

Population
Children and young people with T1D (20 female; 20 CSII; age 14.5 ± 2.9 years; HbA1c 48.9 ± 9.4 mmol/mol)cross-over
Participants
35 children
Comparison
Low-carbohydrate diet vs recommended carbohydrate diet
Primary endpoint
Time in range (CGM)
Methodological detailscross-over
  • Cross-over

Primary result

As reported in the abstract

TIR

P = 0.008

Further findings

Time in hyperglycaemia and average glycaemia

Significantly lower with low-carbohydrate diet (LCD)

Glycaemic variability

No difference between the diets

Body weight and BMI

Significantly lower during LCD

Quality of life (QoL)

No significant differences in self-assessed QoL

Safety

Time in hypoglycaemia

No difference between the diets

LDL-C

No significant difference

Original publication

Low-carbohydrate diet in children and young people with type 1 diabetes: A randomized controlled trial with cross-over design. Diabetes Res Clin Pract. Published 3 September 2024. doi:10.1016/j.diabres.2024.111844

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