Osteoporosis, bone & mineral

Low Bone Mineral Density as a Predictor of Mortality and Infections in Stroke Patients: A Hospital-Based Study

J Clin Endocrinol MetabPublished Retrospective cohort study

Authors' conclusion

Low BMD, particularly in the femur and spine, is a significant predictor of mortality and UTI in stroke patients. These findings highlight the importance of assessing and managing BMD in stroke patients to improve outcomes and reduce complications.

Study context

Population
Stroke patients from a Taiwanese database (2000–2022); average age 76.1 years, 70.5% female; 33.82% osteopenia, 55.25% osteoporosis
Participants
905 patients
Exposure
Lower vs higher bone mineral density (BMD)
Outcome
All-cause mortality
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

All-cause mortality (survival)

Spine BMD threshold below which survival especially reduced

0.842 g/cm²

Right femur BMD threshold below which survival especially reduced

0.624 g/cm²

Observational data: associations, not effects.

Secondary outcomes

Lower spine BMD significantly associated with increased risk of urinary tract infection (UTI)

Original publication

Low Bone Mineral Density as a Predictor of Mortality and Infections in Stroke Patients: A Hospital-Based Study. J Clin Endocrinol Metab. Published 25 May 2024. doi:10.1210/clinem/dgae365

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