Low Bone Mineral Density as a Predictor of Mortality and Infections in Stroke Patients: A Hospital-Based Study
Authors' conclusion
Low BMD, particularly in the femur and spine, is a significant predictor of mortality and UTI in stroke patients. These findings highlight the importance of assessing and managing BMD in stroke patients to improve outcomes and reduce complications.
Study context
- Population
- Stroke patients from a Taiwanese database (2000–2022); average age 76.1 years, 70.5% female; 33.82% osteopenia, 55.25% osteoporosis
- Participants
- 905 patients
- Exposure
- Lower vs higher bone mineral density (BMD)
- Outcome
- All-cause mortality
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
All-cause mortality (survival)
Spine BMD threshold below which survival especially reduced
0.842 g/cm²
Right femur BMD threshold below which survival especially reduced
0.624 g/cm²
Observational data: associations, not effects.
Secondary outcomes
- Lower spine BMD significantly associated with increased risk of urinary tract infection (UTI)
Original publication
Low Bone Mineral Density as a Predictor of Mortality and Infections in Stroke Patients: A Hospital-Based Study. J Clin Endocrinol Metab. Published 25 May 2024. doi:10. 1210/ clinem/ dgae365
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