Diabetes technology

Longitudinal analysis of users transitioning from the Dexcom G5 to the G6 RT‐CGM system in Germany, Sweden and the United Kingdom (2018–2020)

Diabet MedPublished Retrospective observational cohort study

Authors' conclusion

Similar RT-CGM trends were observed across Germany, Sweden, and the UK. Improvements in hypoglycaemia occurred in all countries. The high retention of users may lead to sustained glycaemic benefits associated with RT-CGM use.

Study context

Population
Users in Germany, Sweden and the United Kingdom (UK) who transitioned from Dexcom G5 to G6 between 9–12 months after G6 launched in 2018
Exposure
Dexcom G6 vs Dexcom G5 Real-Time Continuous Glucose Monitoring (RT-CGM)
Outcome
% time in hypoglycaemia, % TIR, user retention rates, device utilisation, and urgent low soon (ULS) alert utilisation
Follow-up
3-month intervals in the 2-year study window
Methodological detailsreal-world anonymised RT-CGM data, multinational (Germany, Sweden, UK)
  • Real-world anonymised RT-CGM data
  • Multinational (Germany, Sweden, UK)

Main finding

As reported in the abstract

Hypoglycaemia, TIR, retention, utilisation
Decrease in median % time <3 mmol/L (54 mg/dL), months 0-3 after transition (range across countries)
0.12-0.28 percentage points
Decrease in median % time <3.9 mmol/L (70 mg/dL), months 0-3 after transition
0.40-0.43 percentage points
Further decrease in % time <3 mmol/L, months 3-6
0.11-0.21 percentage points
Further decrease in % time <3.9 mmol/L, months 3-6
0.34-0.65 percentage points
Retention rate at end of study window
88.8-94.8%
ULS utilisation at end of study window
83.9-86.9%

Observational data: associations, not effects.

Original publication

Longitudinal analysis of users transitioning from the Dexcom G5 to the G6 RT‐CGM system in Germany, Sweden and the United Kingdom (2018–2020). Diabet Med. Published 8 September 2022. doi:10.1111/dme.14946

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