Long-term Continuous Glucose Monitor Use in Very Young Children With Type 1 Diabetes: One-Year Results From the SENCE Study
Authors' conclusion
Over 12 months young children with T1D using newer CGM technology sustained reductions in hypoglycemia and, in contrast to prior studies, persistently wore CGM. However, pervasive hyperglycemia remained unmitigated. This indicates an urgent need for further advances in diabetes technology, behavioral support, and diabetes management educational approaches to optimize glycemia in young children.
Study context
- Population
- Very young children with T1D
- Comparison
- Continuous glucose monitoring (CGM) with family behavioral intervention vs CGM alone vs blood glucose monitoring
Methodological details26-week RCT followed by 26-week extension phase, crossover of blood glucose monitoring (BGM) group to CGM+family behavioral intervention (FBI)
- 26-week RCT followed by 26-week extension phase
- Crossover of BGM group to CGM+FBI
Primary result
As reported in the abstract
Time in range (70-180 mg/dL) · 52 weeks
Baseline CGM+FBI 37% · Standard-CGM 41%
26 weeks BGM-Crossover 38%
Further findings
Hypoglycemia (<70 mg/dL) · 52 weeks
Baseline CGM+FBI 3.4% · Standard-CGM 4.1%
26 weeks BGM-Crossover 4.5%
HbA1c · 52 weeks
Baseline CGM+FBI 8.3% · Standard-CGM 8.2%
26 weeks BGM-Crossover 8.1%
Sensor use · 52-week study visit
- Hypoglycemia (<70 mg/dL) — All three groups sustained decreases in hypoglycemia with CGM use
- P-values <.001
HbA1c · 52 weeks
- HbA1c unchanged with CGM use
Original publication
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