Type 1 diabetes

An RCT of a family intervention for adolescents living with type 1 diabetes: Who benefits most?

Diabet MedPublished Randomised controlled trial

Authors' conclusion

While family dynamics improved for all, adolescents' quality of life improved among youth with fewer resources and from marginalized racial and ethnic backgrounds, whereas parents with higher distress benefited most. For adolescents, socioeconomic context may drive intervention response.

Study context

Population
Adolescents with T1D and their parents (parent-adolescent dyads)
Participants
157 parent-adolescent dyads
Comparison
Family-based programme vs waitlist control
Primary endpoint
% TIR and diabetes health-related quality of life (HRQOL)
Follow-up
3- and 6-month post-baseline
Methodological detailswaitlist control, moderated effects analysis
  • Waitlist control
  • Moderated effects analysis

Primary result

As reported in the abstract

HRQOL (primary outcome) in subgroups

Improved health-related quality of life (HRQOL) with the intervention at 3-month post-baseline among racial and ethnic minoritized adolescents

β = 0.308, p = 0.002, d = 0.81

Improved HRQOL with the intervention at 3-month post-baseline among adolescents not using AID systems

β = 0.261, p = 0.003, d = 0.94

Improved HRQOL with the intervention at 6-month post-baseline among adolescents not using AID systems

β = 0.220, p = 0.005, d = 0.58

Secondary outcomes

OutcomeβP value
Parenting, full sample · immediately after the interventionIntervention vs Waitlist control · parent report of supportive parenting; d = 0.310.151P = 0.007
Parenting, full sample · immediately after the interventionIntervention vs Waitlist control · parent report of unsupportive parenting; d = −0.36−0.177P = 0.002
Parenting, full sample · immediately after the interventionIntervention vs Waitlist control · adolescent report of unsupportive parenting; d = −0.30−0.150P = 0.024
Parent diabetes distress, parents with high baseline distressReduced distress; d = −0.54−0.200P = 0.006

Original publication

An RCT of a family intervention for adolescents living with type 1 diabetes: Who benefits most? Diabet Med. Published 29 October 2025. doi:10.1111/dme.70151

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