Lipids & metabolic liver disease
Linking circulating chemerin and adiponectin to lipoprotein subclasses measured by 1H-NMR spectroscopy in 3199 participants from the study of health in Pomerania
Authors' conclusion
Our highly consistent results demonstrate that high adiponectin was associated with a favorable, anti-atherogenic lipoprotein profile, whereas the opposite was observed for chemerin.
Study context
- Population
- Participants of the Study of Health in Pomerania (SHIP-TREND-0)
- Participants
- 3,199 participants
- Outcome
- Associations between adiponectin/chemerin and lipoprotein subclasses quantified by NMR spectroscopy
Methodological detailspopulation-based, 1H-NMR spectroscopy, adjusted linear regression
- Population-based
- 1H-NMR spectroscopy
- Adjusted linear regression
Main finding
As reported in the abstract
Associations of adiponectin/chemerin with lipoprotein subclasses
- Wide range of significant associations between adiponectin/chemerin and lipoprotein subclasses, primarily in opposite directions
- Higher adiponectin related to lower particle number and lower cholesterol, phospholipid and TG content in atherogenic small, dense LDL particles
- Chemerin positively associated with these small, dense LDL measures
Observational data: associations, not effects.
Original publication
Linking circulating chemerin and adiponectin to lipoprotein subclasses measured by 1H-NMR spectroscopy in 3199 participants from the study of health in Pomerania. Int J Obes (Lond). Published 26 June 2026. doi:10.
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