Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts
Authors' conclusion
Longer duration of breastfeeding was associated with lower risk of CVD in women with type 2 diabetes or GDM.
Study context
- Population
- Parous women with T2D from the Nurses' Health Study I and II (15,146) and women with a history of gestational diabetes mellitus (GDM) from NHS II (4,537)two cohorts
- Exposure
- Lifetime breastfeeding duration >18 months vs 0 months
- Outcome
- Incident CVD: stroke or coronary heart disease (CHD) (MI, coronary revascularization)
- Follow-up
- By 2017
Methodological detailstwo large prospective cohorts, Cox models
- Two large prospective cohorts
- Cox models
Main finding
As reported in the abstract
Incident CVD in women with T2D
Pooled adjusted hazard ratio (95% CI)
>18 monthsvs 0 months
0.68(0.54–0.85)
Per 6-month increment in breastfeeding
0.94(0.91–0.98)
- Incident cardiovascular disease (CVD) cases among women with T2D
- 1,159 during 188,874 person-years
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| CHD in women with T2D | pooled aHR 0.93 (CI 0.88–0.97) | |
| Stroke in women with T2D | aHR 0.96 (CI 0.91–1.02) | |
| Total CVD in women with GDM history | aHR 0.49 (CI 0.28–0.86) | |
| 0.20.5125Ratio (log scale) |
- Total CVD in women with GDM history — Incident CVD cases among women with GDM history
- 132 during 100,218 person-years
Original publication
Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts. Diabetes Care. Published 20 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →