Left atrial remodeling in adolescents with obesity evaluated by speckle-tracking echocardiography
Authors' conclusion
In adolescents with obesity, we observed a specific LA remodeling, including higher volume and lower stiffness, which could constitute early signs of an altered LV diastolic function.
Study context
- Population
- Adolescents with obesity and controls undergoing resting echocardiography with left ventricular (LV) and left atrial (LA) morphology and strain analysis (speckle-tracking echocardiography)
- Participants
- 28 vs 33
- Exposure
- Adolescents with obesity vs controls
- Obesityn = 28
- Controlsn = 33reference
- Outcome
- LA morphology and function by speckle-tracking echocardiography and their determinants
Main finding
As reported in the abstract
- LA volume and stiffness index increased in adolescents with obesity vs controls
- LA reservoir, conduit and booster pump functions not different between groups
Observational data: associations, not effects.
Further findings
Independent determinants of LA volume (stepwise forward multivariate regression)
- Systolic blood pressures, cardiac output and sedimentation rate; β-coefficient
- 0.460, p < 0.0001
Independent determinant of LA stiffness (stepwise forward multivariate regression)
- Only BMI; β-coefficient
- 0.413, p = 0.003
Original publication
Left atrial remodeling in adolescents with obesity evaluated by speckle-tracking echocardiography. Int J Obes (Lond). Published 20 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →