Lack of Association Between Hemoglobin A1c and Continuous Glucose Monitor Metrics Among Individuals with Prediabetes and Normoglycemia
Study context
- Population
- Individuals with T2D, prediabetes or normoglycaemia using CGM
- Participants
- 972 individuals
- Exposure
- Association of hemoglobin A1c (HbA1c) with 8 CGM metrics across glycaemic status
- T2Dn = 421
- Prediabetesn = 319
- Normoglycemian = 232
- Outcome
- Associations between HbA1c and eight CGM metrics
Main finding
As reported in the abstract
Association of mean glucose with HbA1c
| Group | Standardized β | P |
|---|---|---|
| T2D | 0.79 | P < 0.001 |
| Prediabetes | 0.22 | P < 0.001 |
| Normoglycemia | 0.10 | P = 0.022 |
Standardized β
T2D0.79
Prediabetes0.22
Normoglycemia0.10
P
T2DP < 0.001
PrediabetesP < 0.001
NormoglycemiaP = 0.022
- All interaction terms statistically significant
- P < 0.001
Observational data: associations, not effects.
Original publication
Lack of Association Between Hemoglobin A1c and Continuous Glucose Monitor Metrics Among Individuals with Prediabetes and Normoglycemia. Diabetes Technol Ther. Published 1 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →