Real-World Glycemic Improvements with Hybrid Closed Loop Pumps in Youth with Type 1 Diabetes
Authors' conclusion
HbA1c levels decreased in both minority and nonminority youth within 12 months of starting CIQ, and more patients reached the HbA1c target of less than 7%. Disparities in HbA1c between minority and nonminority youth remained and additional studies are warranted to improve this.
Study context
- Population
- Youth with T1D using t:slim X2 pump with Control IQ (CIQ) over 12 months; 50% male, median age 13.3y, median diabetes duration 4.9y
- Participants
- 136 participants
- Exposure
- Hemoglobin A1c (HbA1c) and continuous glucose monitor (CGM) metrics after vs before starting CIQ, minority vs nonminority youth
- Minorityn = 21
- Outcome
- Median HbA1c, before vs after starting CIQ
- Follow-up
- Up to 12 months
Main finding
As reported in the abstract
- Nonminority: median HbA1c decreased from 7.8% to 7.1%
- p < 0.001
- Minority: median HbA1c decreased from 9.8% to 7.8%
- p=0.03
Observational data: associations, not effects.
Further findings
Patients meeting target HbA1c <7%
- Increased from 26% to 45%
TIR and average CGM glucose
- Both nonminority and minority youth had a significant increase in TIR and decrease of average CGM glucose
- P < 0.05
Original publication
Real-World Glycemic Improvements with Hybrid Closed Loop Pumps in Youth with Type 1 Diabetes. Pediatr Diabetes. Published 5 October 2023. doi:10.
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