Automated Insulin Delivery for Minoritized and Nonminoritized Populations With Type 1 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors' conclusion
The AID systems improve glycemic outcomes in minoritized and nonminoritized populations with type 1 diabetes and have good safety profiles. AID systems hold promise for reducing racial and ethnic disparities in diabetes care and outcomes.
Study context
- Population
- Individuals with T1D; databases searched up to August 18, 202512 studies
- Participants
- 327 vs 1,377
- Comparison
- Automated insulin delivery (AID) systems in minoritized vs nonminoritized populations
- Minoritizedn = 327
- Nonminoritizedn = 1,377
- Outcome
- Percentage of TIR (3.9-10.0 mmol/L)
Pooled result
As reported in the abstract
TIR (AID effect, pooled MD)
MD, % (95% CI)P value
MinoritizedI2 = 20%; high certainty
13.90(9.64–18.16)
P < 0.0001NonminoritizedI2 = 15%; high certainty
10.66(9.12–12.21)
P < 0.0001Further pooled results
HbA1c (AID effect, pooled MD)
| MD (%) (95% CI) | ||
|---|---|---|
| Minoritized | −0.49 (−0.69 to −0.29) | |
| Nonminoritized | −0.34 (−0.46 to −0.23) | |
| −1−0.500.5Difference, % (linear scale) |
Safety
Severe hypoglycaemia and DKA
- No significant increase in severe hypoglycemia or DKA
Original publication
Automated Insulin Delivery for Minoritized and Nonminoritized Populations With Type 1 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Endocr Pract. Published 30 September 2025. doi:10.
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