Continuous Glucose Monitoring Frequency and Glycemic Control in People With Type 2 Diabetes
An erratum to this article was published (JAMA Netw Open, 3 Nov 2025 ↗)
Authors' conclusion
This cross-sectional study found that frequent use of CGM (>75% sensor wear) was associated with improved glycemic control compared with infrequent or no use of CGM. These findings suggest that clinicians should monitor CGM use at 6 months, identify potential therapeutic obstacles, and encourage continuous use of CGM.
Study context
- Population
- Adults ≥18 years with T2D and baseline HbA1c 7.0%–15.0%, Optum Market Clarity Data 2019–2023; 45.4% female, mean age 55.9 years
- Participants
- 9,258 adults
- Exposure
- Continuous glucose monitoring (CGM) use frequency vs no CGM use
- Frequency 1n = 1,081
- Frequency 2n = 523
- Frequency 3n = 540
- Frequency 4n = 2,485
- Controln = 4,629reference
- Outcome
- Change in HbA1c by CGM frequency vs no CGM (mixed-model analysis)
- Follow-up
- 12 months
Methodological detailspropensity score-matched, claims and electronic medical record data
- Propensity score-matched
- Claims and electronic medical record data
Main finding
As reported in the abstract
Change in HbA1c
Frequency 4
−1.52
95% CI −1.73–-1.32 · percentage points
Control
−0.63
95% CI −0.80–-0.45 · percentage points
Observational data: associations, not effects.
Further findings
| Outcome | Values | Treatment difference (percentage points) (95% CI) | |
|---|---|---|---|
| HbA1c with addition of GLP-1 RA in frequency 4 · ≈12 monthsFrequency 4vs ControlWith addition of GLP-1 RA | −1.13 (−1.46 to −0.80) | ||
| −2−101Difference, percentage points (linear scale) |
| Outcome | Values |
|---|---|
| Change in HbA1c (greatest reductions) · ≈3 months | Frequency 1 −0.59 (95% CI −0.96–-0.21) percentage points · Frequency 2 −0.57 (95% CI −1.10–-0.05) percentage points · Frequency 3 −0.79 (95% CI −1.25–-0.34) percentage points · Frequency 4 −0.91 (95% CI −1.12–-0.70) percentage points · Control −0.28 (95% CI −0.47–-0.09) percentage points |
Durability of HbA1c improvement
- No further glycemic improvement in frequency 2 and frequency 3 after 6 months
- Improvements in frequency 1 and frequency 4 sustained for the postindex period
Original publication
Continuous Glucose Monitoring Frequency and Glycemic Control in People With Type 2 Diabetes. JAMA Netw Open. Published 1 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →