Ketone Profiles in Community-Dwelling Adults with Type 1 Diabetes Using Continuous Ketone Monitoring
Authors' conclusion
Most community-dwelling adults with type 1 diabetes have ketones <0.6 mmol/L. Glucose levels rose with elevated ketones but were not a diagnostic substitute.
Study context
- Population
- Community-dwelling adults with T1D (PARTNER study run-in); age median 49.8 (IQR 40.2–64.1) yrs; HbA1c median 7.4 (IQR 6.9–8.0)% / 57 (52–64) mmol/mol
- Participants
- 64 adults
- Exposure
- <0.6 mmol/L vs 0.6-0.9 mmol/L vs ≥1.0 mmol/L
- Outcome
- Continuous ketone monitor (CKM) profiles
- Follow-up
- Two weeks
Methodological detailsanalysis of run-in data, two-week continuous ketone monitoring
- Analysis of run-in data
- Two-week continuous ketone monitoring
Main finding
As reported in the abstract
Peak ketone category · two-week run-in
| Group | Value | Maximum time-in-range 0.6-0.9 mmol/L | Maximum time-in-range ≥1.0 mmol/L |
|---|---|---|---|
| <0.6 mmol/L | 61% | ||
| 0.6-0.9 mmol/L | 23% | 5.3% | |
| ≥1.0 mmol/L | 16% | 2.4% |
Value
<0.6 mmol/L61%
0.6-0.9 mmol/L23%
≥1.0 mmol/L16%
Maximum time-in-range 0.6-0.9 mmol/L
<0.6 mmol/L— not stated in the abstract
0.6-0.9 mmol/L5.3%
≥1.0 mmol/L— not stated in the abstract
Maximum time-in-range ≥1.0 mmol/L
<0.6 mmol/L— not stated in the abstract
0.6-0.9 mmol/L— not stated in the abstract
≥1.0 mmol/L2.4%
Observational data: associations, not effects.
Further findings
| Outcome | Difference (mg/dL) (95% CI) | P value | |
|---|---|---|---|
| Median glucose during CKM ketones ≥1.0 mmol/Lvs time-matched control periods <0.6 mmol/LOn average higher | 47 (19–73) | P = 0.001 | |
| −50050100Difference, mg/dL (linear scale) |
Original publication
Ketone Profiles in Community-Dwelling Adults with Type 1 Diabetes Using Continuous Ketone Monitoring. Diabetes Technol Ther. Published 12 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →