Association Between Celiac Disease and Uncontrolled Hemoglobin A1c Levels in Type 1 Diabetes Pediatric Patients
Main finding · Uncontrolled HbA1c (≥7%)Result — go to the resultAdjusted odds ratio 2.59 95% CI 1.37–4.90Authors' conclusion
CD is significantly associated with poorer glycemic control in pediatric patients with T1D, independent of age, race, and sex. These findings suggest the need for closer monitoring, individualized dietary counseling, and targeted interventions in this high-risk group.
Study context
- Population
- Pediatric patients (<18 years) diagnosed with T1D 2012–2023, Corewell Health East
- Participants
- 2,203 patients
- Exposure
- Celiac disease (CD) vs no CD in pediatric T1D
- CDn = 101
- Outcome
- Uncontrolled HbA1c (≥7%)
Methodological detailsretrospective chart review
- Retrospective chart review
Main finding
As reported in the abstract
Adjusted odds ratio
2.59
95% CI 1.37–4.90
P = 0.003
By group
CDvs No CD
aOR 2.59 (95% CI 1.37–4.90); P = 0.003
Observational data: associations, not effects.
Further findings
Age at T1D diagnosis
P < 0.0001
Age at T1D diagnosis
- CD patients had more Hemoglobin A1c (HbA1c) measurements
Other factors for uncontrolled diabetes
- Younger age and Black race also associated with higher odds of uncontrolled diabetes
Original publication
Association Between Celiac Disease and Uncontrolled Hemoglobin A1c Levels in Type 1 Diabetes Pediatric Patients. Pediatr Diabetes. Published 11 February 2026. doi:10.
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