Joint pain, physical function, and balance self-confidence in acromegaly versus nonfunctioning pituitary adenoma patients
Authors' conclusion
We confirmed an increased prevalence of falls in both groups with diminished balance confidence in PWA. This reduced balance self-confidence seems to be related to their increased hip functional impairment in comparison with PNA.
Study context
- Population
- Patients with acromegaly and patients with nonfunctioning pituitary adenoma of similar age, sex and BMI, from two Canadian tertiary care centers
- Participants
- 94 vs 82
- Exposure
- Acromegaly vs nonfunctioning pituitary adenoma
- Patients with acromegaly (PWA)n = 94
- PNAn = 82reference
- Outcome
- Prevalence of falls (past 12 months) and balance self-confidence
- Follow-up
- Past 12 months
Methodological detailscase-controlled, tertiary care centers, two Canadian centers
- Case-controlled
- Tertiary care centers
- Two Canadian centers
Main finding
As reported in the abstract
- Similarly high risk of falls in PWA and PNA
- PWA had lower self-confidence to maintain balance
- PWA vs PNA: P < 0.01
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Joint pain and functional impairment (upper extremity, hip, knee, ankle) | all P < .01 |
- Joint pain and functional impairment (upper extremity, hip, knee, ankle): higher joint pain scores and more functional impairment with PWA
Predictors of balance self-confidence
- In both groups, age, sex and ankle functional score were predictors
- PWA: hip functional score also a predictor; PNA: knee and back pain scores were predictors
Original publication
Joint pain, physical function, and balance self-confidence in acromegaly versus nonfunctioning pituitary adenoma patients. Eur J Endocrinol. Published 20 July 2023. doi:10.
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