Is serum 25‐hydroxyvitamin D deficiency a risk factor for the incidence of slow gait speed in older individuals? Evidence from the English longitudinal study of ageing
Main finding · Incidence of slownessResult — go to the resultIncidence rate ratio 1.22 95% CI 1.01–1.49Authors' conclusion
Serum 25(OH)D deficiency is a risk factor for the incidence of slowness in older individuals, suggesting that maintaining sufficient 25(OH)D levels could be a strategic approach to minimise long-term mobility impairment.
Study context
- Population
- Adults aged ≥60 years with baseline gait speed >0.8 m/s, English Longitudinal Study of Ageing (ELSA)ELSA
- Participants
- 2,815 adults
- Exposure
- Serum 25D deficiency or insufficiency vs sufficiency
- Outcome
- Incident slowness (walking speed ≤0.8 m/s)
- Follow-up
- Six years
Methodological detailslongitudinal, 6-year follow-up, Poisson regression adjusted for sociodemographic, behavioural and clinical characteristics
- Longitudinal
- 6-year follow-up
- Poisson regression adjusted for sociodemographic, behavioural and clinical characteristics
Main finding
Incidence of slowness · 6-year follow-up
Incidence rate ratio
1.22
95% CI 1.01–1.49
By group
Sufficiency
67.4 per 1000 person-years
95% CI 60.93–74.64
Insufficiency
76.7 per 1000 person-years
95% CI 68.30–86.22
Deficiency
90.7 per 1000 person-years
95% CI 78.46–104.92
Deficiencyvs Sufficiency
IRR 1.22 (95% CI 1.01–1.49)
As reported in the abstract
Observational data: associations, not effects.
Original publication
Is serum 25‐hydroxyvitamin D deficiency a risk factor for the incidence of slow gait speed in older individuals? Evidence from the English longitudinal study of ageing. Diabetes Obes Metab. Published 13 March 2025. doi:10.
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