Does the Combination of Abdominal Obesity and Vitamin D Deficiency Increase the Risk of Death in Individuals Aged 50 or Older? Evidence From the ELSA Study
Authors' conclusion
AO combined with 25(OH)D deficiency increases mortality risk in older adults.
Study context
- Population
- Adults aged ≥ 50 years from the ELSA Study
- Participants
- 5,520 adults
- Exposure
- Combinations of abdominal obesity status and 25D status vs NAO/VDS
- Outcome
- Mortality (risk of death)
- Follow-up
- 6 years
Methodological details6-year follow-up, Cox regression adjusted for sociodemographic, behavioural and clinical characteristics
- 6-year follow-up
- Cox regression adjusted for sociodemographic, behavioural and clinical characteristics
Main finding
As reported in the abstract
Risk of death
Each group vs NAO/VDSHazard ratio (95% CI)
NAO/VDI
1.91(1.37–2.66)
NAO/VDD
1.81(1.25–2.62)
AO/VDS
1.47(1.02–2.14)
AO/VDI
1.50(1.01–2.23)
AO/VDDhighest mortality risk
2.23(1.50–3.33)
Observational data: associations, not effects.
Original publication
Does the Combination of Abdominal Obesity and Vitamin D Deficiency Increase the Risk of Death in Individuals Aged 50 or Older? Evidence From the ELSA Study. Diabetes Obes Metab. Published 6 May 2026. doi:10.
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