Is adiposity associated with white matter microstructural health and intelligence differently in males and females?
Authors' conclusion
Taken together, these findings suggest that there are inherent sex-driven differences in how brain health is associated with obesity.
Study context
- Population
- UK Biobank participants
- Exposure
- Males vs females
- Outcome
- Associations of adiposity (abdominal fat ratio, liver proton density fat fraction) with brain health (intelligence, white matter microstructure by DTI), by sex
Main finding
As reported in the abstract
Association of adiposity with intelligence and DTI metrics
- Intelligence and DTI metrics are associated with adiposity differently in males and females
Observational data: associations, not effects.
Further findings
- Sex differences distinct from those in associations of DTI metrics with age and blood pressure
Original publication
Is adiposity associated with white matter microstructural health and intelligence differently in males and females? Obesity (Silver Spring). Published 8 March 2023. doi:10.
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