Obesity

Deriving sex-specific anthropometric cut-points for obesity and cardiovascular disease risk in Qatari adults

Int J Obes (Lond)Published Cross-sectional study

Authors' conclusion

These results highlighted the differences of global anthropometric thresholds and the need for population-specific measures to improve obesity and CVD risk classification in an Arab sample. Our study derived tailored cut-points for clinical and public health use in Qatar, as a tool to improve screening and diagnostics for timely obesity and disease intervention in this population.

Study context

Population
Qatari adults from the Qatar Biobank (QBB); relatively young adults with high levels of adiposity
Participants
6,000 adults
Exposure
ROC-derived sex-specific anthropometric cut-points vs World Health Organization (WHO)-recommended cut-points
Outcome
Optimal sex-specific anthropometric cut-points aligned with body fat percentage (%BF) and disease-specific thresholds for elevated blood pressure, diabetes and dyslipidemia
Methodological detailsROC curve analyses, misclassification analyses
  • ROC curve analyses
  • Misclassification analyses

Main finding

As reported in the abstract

Optimal anthropometric cut-points (ROC-derived)

Optimal body mass index (BMI) cut point, males

25.2 kg/m²

Optimal BMI cut point, females

24.8 kg/m²

WC cut-point, males (lower than global standards)

84.3 cm

WC cut-point, females (lower than global standards)

74.5 cm

Observational data: associations, not effects.

Further findings

Misclassification using WHO cut-points

Misclassified using WHO BMI cut point, males
54.6%
Misclassified using WHO BMI cut point, females
43.0%
Females with obesity by %BF misclassified without obesity using WHO WC thresholds
87.5%

Original publication

Deriving sex-specific anthropometric cut-points for obesity and cardiovascular disease risk in Qatari adults. Int J Obes (Lond). Published 10 December 2025. doi:10.1038/s41366-025-01947-7

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