Intermittently Scanned Continuous Glucose Monitoring Enhances Weight Loss and Adherence in Women with Obesity: A Randomized Controlled Trial
Authors' conclusion
Integrating isCGM into lifestyle interventions enhances adherence and supports clinically significant improvements in body composition and glycemic control among women with obesity.
Study context
- Population
- Women with overweight or obesity (BMI > 25 kg/m²); both groups had supervised exercise (3 sessions/week) and identical dietary counseling
- Participants
- 35 women
- Comparison
- Intermittently scanned continuous glucose monitoring (isCGM) at baseline, mid-intervention and study end vs isCGM only at baseline and end, alongside supervised exercise and dietary counseling
- Interventionn = 17
- Controln = 18reference
- Primary endpoint
- Changes in body weight and BMI
- Follow-up
- 12 weeks
Primary result
As reported in the abstract
Change in body weight
Intervention
−5.5
± 2.3 · kg
Control
−0.2
± 1.8 · kg
P < 0.001
Secondary outcomes
Clinically meaningful weight loss (≥3% BMI and body fat reduction)
| Outcome | Intervention | Control | P value |
|---|---|---|---|
| Change in BMI (primary outcome) · 12 weeks | −1.9 ± 0.6 kg/m² | −0.1 ± 0.4 kg/m² | P < 0.001 |
- Waist-to-height ratio, body fat, visceral fat, muscle mass and dietary adherence
- P < 0.05
Waist-to-height ratio, body fat, visceral fat, muscle mass and dietary adherence
- Significantly greater reductions in waist-to-height ratio, body fat and visceral fat, increased muscle mass and improved dietary adherence with intervention vs controls
TIR
- TIR improved modestly in the intervention group
- P = 0.03
Original publication
Intermittently Scanned Continuous Glucose Monitoring Enhances Weight Loss and Adherence in Women with Obesity: A Randomized Controlled Trial. Diabetes Technol Ther. Published 17 February 2026. doi:10. 1177/ 15209156261423952
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