Intermittently scanned continuous glucose monitoring compared with blood glucose monitoring is associated with lower HbA1c and a reduced risk of hospitalisation for diabetes-related complications in adults with type 2 diabetes on insulin therapies
Authors' conclusion
This study shows that Swedish adults with type 2 diabetes on insulin who are using isCGM have a significantly reduced HbA1c and fewer hospital admissions for diabetes-related complications compared with BGM control participants.
Study context
- Population
- Adults with insulin-treated T2D in Sweden with intermittently scanned continuous glucose monitoring (isCGM) initiation after 1 June 2017 (National Diabetes Register)matched cohort
- Exposure
- isCGM vs capillary blood glucose monitoring (BGM)
- Outcome
- Change in HbA1c (baseline-adjusted)
- Follow-up
- 6 months
Methodological detailscomparative, matched controls, National Diabetes Register
- Comparative
- Matched controls
- National Diabetes Register
Main finding
As reported in the abstract
Baseline-adjusted difference in change
−3.7 mmol/mol
isCGM T2D-MDI vs BGM T2D-MDI · −0.34%; maintained at 24 months
Baseline-adjusted difference in change
−3.5 mmol/mol
isCGM T2D-B vs BGM T2D-B · −0.32%; maintained at 24 months
Observational data: associations, not effects.
Further findings
| Outcome | RR (95% CI) | |
|---|---|---|
| Hospital admissions, T2D-MDI cohortisCGM T2D-MDIvs BGM T2D-MDISevere hypoglycaemia | 0.51 (0.27–0.95) | |
| Hospital admissions, T2D-MDI cohortisCGM T2D-MDIvs BGM T2D-MDIStroke | 0.54 (0.39–0.73) | |
| Hospital admissions, T2D-MDI cohortisCGM T2D-MDIvs BGM T2D-MDIAcute non-fatal MI | 0.75 (0.57–0.99) | |
| Hospital admissions, T2D-MDI cohortisCGM T2D-MDIvs BGM T2D-MDIHospitalisation for any reason | 0.84 (0.77–0.90) | |
| Hospital admissions, T2D-B cohortisCGM T2D-Bvs BGM T2D-BHeart failure | 0.63 (0.46–0.87) | |
| Hospital admissions, T2D-B cohortisCGM T2D-Bvs BGM T2D-BHospitalisation for any reason | 0.76 (0.69–0.84) | |
| 0.20.5125Relative risk (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Intermittently scanned continuous glucose monitoring compared with blood glucose monitoring is associated with lower HbA1c and a reduced risk of hospitalisation for diabetes-related complications in adults with type 2 diabetes on insulin therapies. Diabetologia. Published 26 October 2024. doi:10.
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