Initiation of Intermittently Scanned Continuous Glucose Monitoring Is Associated With Reduced Hospitalization for Acute Diabetes Events and Cardiovascular Complications in Adults With Type 1 Diabetes
Authors' conclusion
This study shows that adults with type 1 diabetes in Sweden who initiate isCGM have significantly reduced hospitalization rates for acute diabetes events, kidney disease, and cardiovascular complications, along with improved glucose control, compared with BGM users.
Study context
- Population
- Adults with T1D in Sweden, isCGM index date after 1 June 2017, HbA1c baseline 3–8 months before index date
- Participants
- 11,822 vs 3,007
- Exposure
- isCGM vs blood glucose monitoring
- isCGMn = 11,822
- Blood glucose monitoring (BGM)n = 3,007reference
- Outcome
- Hospitalization rates for metabolic and vascular complications of diabetes (per 100 person-years) and HbA1c
Methodological detailsmatched controls, Swedish National Diabetes Register and National Patient Register
- Matched controls
- Swedish National Diabetes Register and National Patient Register
Main finding
As reported in the abstract
Hospitalization (relative risk, isCGM vs BGM)
isCGM vs BGMRelative risk (95% CI)
Hypoglycemia
0.32(0.14–0.74)
DKA
0.55(0.35–0.87)
Stroke
0.48(0.37–0.64)
Acute MI
0.64(0.46–0.91)
AF
0.59(0.38–0.94)
HF
0.25(0.16–0.39)
Peripheral vascular disease
0.21(0.07–0.62)
Kidney disease
0.48(0.35–0.66)
Any reason
0.32(0.29–0.35)
Observational data: associations, not effects.
Further findings
| Outcome | Difference, % | P value |
|---|---|---|
| Change in mean HbA1c · 6 months | −0.30 (−3.3 mmol/mol) | P < 0.001 |
| Change in mean HbA1c · 24 months | −0.24 (−2.6 mmol/mol) | P < 0.001 |
Original publication
Initiation of Intermittently Scanned Continuous Glucose Monitoring Is Associated With Reduced Hospitalization for Acute Diabetes Events and Cardiovascular Complications in Adults With Type 1 Diabetes. Diabetes Care. Published 24 September 2024. doi:10. 2337/ dc24-0690
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