Interleukin‐6 is not involved in appetite regulation following moderate‐intensity exercise in males with normal weight and obesity
Authors' conclusion
These results suggest that IL-6 is not involved in exercise-induced appetite suppression. Despite blunted appetite-regulatory peptide responses to MICT in participants with OB, NW participants exhibited decreased acylated ghrelin; however, no differences in appetite perceptions existed between CTRL and MICT or NW and OB.
Study context
- Population
- Sedentary males with normal weight and with obesity
- Comparison
- Moderate-intensity continuous training (MICT) vs non-exercise control, in normal weight (NW) vs obesity (OB)
- NWn = Ninereference
- OBn = eight
- Primary endpoint
- Role of IL-6 in exercise-induced appetite regulation (IL-6, acylated ghrelin, PYY3-36, GLP-1, appetite perceptions)
- Follow-up
- Fasted, pre exercise, and 30, 90, and 150 minutes post exercise
Primary result
As reported in the abstract
- IL-6 did not moderate/mediate acylated ghrelin release after exercise
- p > 0.251
Further findings
- No observable effects of MICT on PYY3-36, GLP-1 or overall appetite
- P > 0.334, η p 2 < 0.062
Original publication
Interleukin‐6 is not involved in appetite regulation following moderate‐intensity exercise in males with normal weight and obesity. Obesity (Silver Spring). Published 8 August 2023. doi:10.
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