Impact of a multicomponent healthcare intervention on glycaemic control in subjects with poorly controlled type 2 diabetes: The INTEGRA study
Primary result · HbA1c reductionResult — go to the resultMean difference −0.62 % 95% CI −0.2% to −1.04%Authors' conclusion
A multicomponent intervention including a dedicated visit oriented at reducing therapeutic inertia by primary care physicians can improve glycaemic control in poorly controlled patients with type 2 diabetes.
Study context
- Population
- Subjects with T2D and HbA1c >9% (>75 mmol/mol) from 11 primary care centres; mean age 59.5 years, mean diabetes duration 10.7 years, mean HbA1c 10.3% (89.0 mmol/mol)
- Participants
- 225 vs 181
- Comparison
- Multicomponent healthcare intervention with dedicated visit vs sham control
- Interventionn = 225
- Sham controln = 181reference
- Primary endpoint
- Reduction in HbA1c between groups
- Follow-up
- 12 months
Methodological detailscluster, non-randomized, pragmatic, 11 primary care centres
- Cluster
- Non-randomized
- Pragmatic
- 11 primary care centres
Primary result
HbA1c reduction
Mean difference
−0.62 %
95% CI −0.2% to −1.04%
P = 0.002
As reported in the abstract
Further findings
HbA1c <8% · 12 months
P = 0.003
Treated with >3 antidiabetic therapies · 12 months
P = 0.0008
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| HbA1c <8% · 12 months | 2.52 (1.54–4.12) | P < 0.001 | |
| 0.20.5125Odds ratio (log scale) |
- HbA1c <8%: intervention was the only variable associated with higher odds of HbA1c <8%
Original publication
Impact of a multicomponent healthcare intervention on glycaemic control in subjects with poorly controlled type 2 diabetes: The INTEGRA study. Diabetes Obes Metab. Published 3 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →