Gestational diabetes & diabetes in pregnancy

Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Gestational Diabetes Mellitus Risk

J Clin Endocrinol MetabPublished Prospective cohort study

Authors' conclusion

Utilizing both empirical dietary indexes, EDIP and EDIH, might offer a potentially more effective approach in preventing GDM when compared to solely focusing on adherence to the MD pattern.

Study context

Population
Pregnant women, Maternal and Infant Health cohort, Hefei, China (2015–2021); diet by food frequency questionnaire
Participants
8,495 women
Exposure
Highest vs lowest quartiles of empirical dietary index for hyperinsulinemia (EDIH), empirical dietary inflammatory pattern (EDIP) and MD score
Outcome
GDM by 2-hour 75-gram OGTT
Follow-up
24 to 28 weeks of gestation

Main finding

As reported in the abstract

GDM
Odds ratio (95% CI)
EDIH highest quartilevs EDIH lowest quartile
1.39(1.30–1.49)
EDIP highest quartilevs EDIP lowest quartile
2.40(1.88–3.01)
MD lowest quartilevs MD highest quartile
1.33(1.14–1.55)

Observational data: associations, not effects.

Further findings

Prediction of gestational diabetes mellitus (GDM) by combined EDIP and EDIH (ROC)

AUC, EDIP + EDIH combined
0.81 (95% CI, 0.78-0.82; P = .003)

Original publication

Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Gestational Diabetes Mellitus Risk. J Clin Endocrinol Metab. Published 13 April 2024. doi:10.1210/clinem/dgae238

Composed by AI from the published abstract and checked against it. How Briefs are made →

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