Gestational diabetes & diabetes in pregnancy
Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Gestational Diabetes Mellitus Risk
Authors' conclusion
Utilizing both empirical dietary indexes, EDIP and EDIH, might offer a potentially more effective approach in preventing GDM when compared to solely focusing on adherence to the MD pattern.
Study context
- Population
- Pregnant women, Maternal and Infant Health cohort, Hefei, China (2015–2021); diet by food frequency questionnaire
- Participants
- 8,495 women
- Exposure
- Highest vs lowest quartiles of empirical dietary index for hyperinsulinemia (EDIH), empirical dietary inflammatory pattern (EDIP) and MD score
- Outcome
- GDM by 2-hour 75-gram OGTT
- Follow-up
- 24 to 28 weeks of gestation
Main finding
As reported in the abstract
GDM
Odds ratio (95% CI)
EDIH highest quartilevs EDIH lowest quartile
1.39(1.30–1.49)
EDIP highest quartilevs EDIP lowest quartile
2.40(1.88–3.01)
MD lowest quartilevs MD highest quartile
1.33(1.14–1.55)
Observational data: associations, not effects.
Further findings
Prediction of gestational diabetes mellitus (GDM) by combined EDIP and EDIH (ROC)
- AUC, EDIP + EDIH combined
- 0.81 (95% CI, 0.78-0.82; P = .003)
Original publication
Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Gestational Diabetes Mellitus Risk. J Clin Endocrinol Metab. Published 13 April 2024. doi:10. 1210/ clinem/ dgae238
Composed by AI from the published abstract and checked against it. How Briefs are made →