Increased Prevalence of Binge Eating Disorder and Bulimia Nervosa in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
Pooled result · Any eating disorderResult — go to the resultOdds ratio 1.53 CI 1.29–1.82Authors' conclusion
Our study informs the 2023 PCOS Guideline recommendations for consideration of the risk of disordered eating/ eating disorders in care of women with PCOS, regardless of weight, especially during providing lifestyle counseling.
Study context
- Population
- Adolescent or adult women with and without polycystic ovary syndrome (PCOS); databases searched from inception through February 1, 202420 studies
- Participants
- 28,922 vs 258,619
- Comparison
- Women with PCOS vs controls
- PCOSn = 28,922
- Controlsn = 258,619reference
- Outcome
- Prevalence of disordered eating/eating disorders
Methodological detailsrandom effects meta-analysis, Grading of Recommendations, Assessment, Development and Evaluations (GRADE) quality assessment, risk of bias assessment, Most included studies were of moderate quality, with no evidence of publication bias
- Random effects meta-analysis
- GRADE quality assessment
- Risk of bias assessment
- Most included studies were of moderate quality, with no evidence of publication bias
Pooled result
Any eating disorder
Odds ratio
1.53
CI 1.29–1.82
PCOSvs Controls
OR 1.53 (CI 1.29–1.82)
As reported in the abstract
Further pooled results
| Outcome | OR (CI) | |
|---|---|---|
| Any eating disorder, PCOS diagnosed by Rotterdam criteria4 studies | 2.88 (1.55–5.34) | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | SMD (CI) | |
|---|---|---|
| Mean disordered eating scores | 0.52 (0.28–0.77) | |
| −0.500.51Difference (linear scale) |
- Mean disordered eating scores: 13 studies; higher in PCOS, including when stratified by normal and higher weight BMI
Bulimia nervosa, binge eating disorder, disordered eating, anorexia nervosa
- Odds of bulimia nervosa, binge eating disorder and disordered eating, but not anorexia nervosa, were increased in PCOS
Original publication
Increased Prevalence of Binge Eating Disorder and Bulimia Nervosa in Women With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. Published 8 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →