Effect of Weight Loss Interventions on the Symptomatic Burden and Biomarkers of Polycystic Ovary Syndrome : A Systematic Review of Randomized Controlled Trials
Authors' conclusion
Weight loss interventions were associated with improvements in some important features of PCOS and should be considered as a routine treatment option for people with PCOS.
Study context
- Population
- People with polycystic ovary syndrome (PCOS); databases searched from inception through June 202429 comparisons
- Participants
- 1,529 people
- Comparison
- Weight loss interventions vs usual care
- Outcome
- Clinical features of PCOS
Methodological detailsrandom-effects meta-analysis with Knapp-Hartung adjustment
- Random-effects meta-analysis with Knapp-Hartung adjustment
Pooled result
As reported in the abstract
Weight loss interventions vs Usual careMD (CI)
HOMA-IR; I2 = 24%
−0.45(−0.75 to −0.15)
FAI; I2 = 48%
−2.03(−3.0 to −1.07)
Menstrual frequency; I2 = 43%
2.64(0.65–4.63)
Original publication
Effect of Weight Loss Interventions on the Symptomatic Burden and Biomarkers of Polycystic Ovary Syndrome : A Systematic Review of Randomized Controlled Trials. Ann Intern Med. Published 5 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →