Implementation of a Spanish-language, direct-to-patient primary aldosteronism testing program
Authors' conclusion
This Spanish-language, direct-to-patient PA testing program effectively reached patients for testing, identified possible PA in over 30%, and influenced downstream care. Language-concordant PA testing initiatives can help to address the high prevalence of hypertension and PA in the US Hispanic/Latino population.
Study context
- Population
- Spanish-speaking adults with primary aldosteronism (PA) testing indications recruited from Boston, New York, Miami, Houston and Los Angeles/San Diego; 77.4% with limited English proficiency
- Participants
- 155 adults
- Outcome
- Frequency of a positive PA test
Methodological detailssingle-group, direct-to-patient, Spanish-language, multicity, 6-month follow-up, Virtual medical history review in Spanish and local phlebotomy for PA testing; laboratory interpretations communicated to patients and clinicians
- Single-group
- Direct-to-patient
- Spanish-language
- Multicity
- 6-month follow-up
- Virtual medical history review in Spanish and local phlebotomy for PA testing; laboratory interpretations communicated to patients and clinicians
Main finding
As reported in the abstract
Positive PA test
Tested positive for PA
30.3%
Secondary outcomes
Clinical action among PA-positive participants with follow-up · 6 months
- Underwent additional testing for PA
- 10.3%
- Started a mineralocorticoid receptor antagonist
- 10.3%
- n = 29 tested positive and provided follow-up
Barriers and participant experience
- Access to care and clinician dismissal of results cited as barriers to clinical action
- Participation positively rated to enhance health awareness and interest in research participation
Original publication
Implementation of a Spanish-language, direct-to-patient primary aldosteronism testing program. J Clin Endocrinol Metab. Published 10 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →