Impact of lifestyle moderate‐to‐vigorous physical activity timing on glycemic control in sedentary adults with overweight/obesity and metabolic impairments
Authors' conclusion
These findings suggest that timing of lifestyle MVPA is significant. Specifically, accumulating more MVPA during the evening appears to have a beneficial effect on glucose homeostasis in sedentary adults with overweight/obesity and metabolic impairments.
Study context
- Population
- Sedentary adults with overweight/obesity and at least one metabolic impairment; 50% women; age 46.8 (SD 6.2) years; BMI 32.9 (SD 3.5) kg/m²
- Participants
- 186 adults
- Exposure
- Moderate-to-vigorous physical activity (MVPA) timing vs inactive days
- Outcome
- Daily glycemic control (24-h, diurnal and nocturnal mean glucose by CGM)
- Follow-up
- 14-day monitoring
Main finding
As reported in the abstract
Mean glucose levels, evening vs inactive
Evening vs InactiveMean difference, mg/dL (95% CI)
24-h mean glucose
−1.26(−2.2 to −0.4)
Diurnal mean glucose
−1.10(−2.0 to −0.2)
Nocturnal mean glucose
−2.16(−3.5 to −0.8)
Observational data: associations, not effects.
Further findings
Subgroups: impaired glucose regulation; sex
- Association stronger in participants with impaired glucose regulation
- Pattern of associations similar in men and women
Original publication
Impact of lifestyle moderate‐to‐vigorous physical activity timing on glycemic control in sedentary adults with overweight/obesity and metabolic impairments. Obesity (Silver Spring). Published 10 June 2024. doi:10.
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