Type 1 diabetes

Impact of Evolving Life Circumstances on Emerging Adults with Type 1 Diabetes: Discoveries from the Tübingen Transition Study after 22 Years

Horm Res PaediatrPublished Cohort study with mixed cross-sectional longitudinal analysis

Authors' conclusion

Psychosocial life circumstances that are considered more stable in early adulthood, such as being a parent and working in academic occupation, were positively associated with metabolic control.

Study context

Population
Patients with childhood-onset T1D transferred from pediatric to adult care between 1998 and 2021 (Tübingen Transition Study)205 responded at least once
Participants
281 patients
Outcome
Factors associated with metabolic control (HbA1c) following transfer to adult care
Methodological detailsyearly questionnaire, mixed cross-sectional longitudinal approach
  • Yearly questionnaire
  • Mixed cross-sectional longitudinal approach

Main finding

As reported in the abstract

Factors associated with HbA1c · before and after transfer
Vocational training vs studies: differences most pronounced; 7.4 ± 1.0%, 57 ± 13 mmol/mol vs 7.0 ± 0.8%, 53 ± 15 mmol/mol
p < 0.05

Observational data: associations, not effects.

Further findings

Pump therapy by sex

Women more frequently treated with pump therapy than men
P < 0.05

Having children, aged 30-40: T1D vs general population

Lower prevalence with T1D vs general population
38.0% vs. 52.7%

Being married, aged 30-40: T1D vs general population

Lower prevalence with T1D vs general population
40.5% vs. 55.3%

Original publication

Impact of Evolving Life Circumstances on Emerging Adults with Type 1 Diabetes: Discoveries from the Tübingen Transition Study after 22 Years. Horm Res Paediatr. Published 11 December 2025. doi:10.1159/000550023

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