Type 2 & other diabetes

Impact of Continuous Glucose Monitoring Versus Blood Glucose Monitoring to Support a Carbohydrate-Restricted Nutrition Intervention in People with Type 2 Diabetes

Diabetes Technol TherPublished Randomised controlled trial

Authors' conclusion

Both the CGM and BGM arms saw similar and significant improvements in glycemia and other diabetes-related outcomes during this MSKDP.

Study context

Population
Adults with T2D; mean (SD) T2D duration 9.7 (7.7) years, HbA1c 8.1% (1.2%)
Participants
163 adults
Comparison
Continuous glucose monitoring (CGM) vs blood glucose monitoring (BGM) to guide a medically supervised ketogenic diet program
  • CGMn = 81
  • BGMn = 82reference
Primary endpoint
Difference in change in TIR between CGM and BGM during a MSKDP
Methodological detailsremote care
  • Remote care

Primary result

As reported in the abstract

TIR · Base to M3

CGM

61-89%

BGM

63%-85%

P = 0.26

Time in range (TIR) improved from baseline (Base) to M3
P < 0.001

Further findings

Additional CGM metrics · M1 through M3

Improved by M1, sustained through M3

HbA1c · Base to M3

HbA1c decreased by ≥1.5% in both CGM and BGM arms
P < 0.001

Diabetes medications · Base to M3

De-intensified based on change in medication effect scores
P < 0.001

Total energy and carbohydrate intake

Decreased
P < 0.001

Weight

Clinically significant weight loss in both arms
P < 0.001

Original publication

Impact of Continuous Glucose Monitoring Versus Blood Glucose Monitoring to Support a Carbohydrate-Restricted Nutrition Intervention in People with Type 2 Diabetes. Diabetes Technol Ther. Published 11 November 2024. doi:10.1089/dia.2024.0406

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