Type 2 & other diabetes

Effects of Continuous Glucose Monitoring Versus Blood Glucose Monitoring During a Carbohydrate-Restricted Nutrition Intervention in People With Type 2 Diabetes: 6-Month Follow-up Outcomes From a Randomized Clinical Trial

Endocr PractPublished Randomised controlled trial

Authors' conclusion

The CGM and BGM arms achieved similar and significant improvements in glycemia and other diabetes-related outcomes after 6 months in this MSKDP.

Study context

Population
Adults with T2D; mean (SD) T2D duration 9.7 (7.7) years, HbA1c 8.1% (1.2%)
Participants
163 adults
Comparison
Continuous glucose monitoring (CGM) vs blood glucose monitoring (BGM) during a virtual medically supervised ketogenic diet program
  • CGMn = 81
  • BGMn = 82reference

Primary result

As reported in the abstract

TIR · Base to M6
Within-arm improvement
P < .001

Further findings

HbA1c · baseline (Base) to M6

HbA1c decreased at least 1.3% in both arms
P < 0.001

Diabetes medications · Base to M6

Deintensified in both arms based on medication effect scores
P < 0.01

Energy and carbohydrate intake · Base to M6

Energy and carbohydrate intake decreased
P < 0.001

Weight · Base to M6

Clinically meaningful weight loss in both arms
P < 0.001

Original publication

Effects of Continuous Glucose Monitoring Versus Blood Glucose Monitoring During a Carbohydrate-Restricted Nutrition Intervention in People With Type 2 Diabetes: 6-Month Follow-up Outcomes From a Randomized Clinical Trial. Endocr Pract. Published 2 June 2025. doi:10.1016/j.eprac.2025.05.746

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