Reducing Inpatient Hypoglycemia: A Diversified Approach to a Complex Problem
Authors' conclusion
Through a multipronged approach consisting of three unique QI interventions - each targeting one aspect of inpatient insulin management - our academic institution was able to significantly reduce the number of inpatient hypoglycemic events.
Study context
- Population
- Nonobstetrics patients ≥ 19 years of age receiving scheduled insulin at a tertiary hospital
- Comparison
- After vs before implementation of three QI interventions targeting basal, prandial and correction insulin
- Outcome
- Incidence of hypoglycemia: unique patients with a hypoglycemic event per month divided by all admissions that month
Methodological detailsbefore-and-after comparison, single-centre, tertiary hospital
- Before-and-after comparison
- Single-centre
- Tertiary hospital
Main finding
As reported in the abstract
Incidence of hypoglycemia, by insulin component
- After vs Before: P = 0.02
- After vs Before: P < 0.001
- After vs Before: P = 0.25
Further findings
| Outcome | P value |
|---|---|
| Basal insulin-associated hypoglycemia, subgroup with hospital-associated hyperglycemia and T2D (excluding T1D or cystic fibrosis-related diabetes)Significant decrease after | P = 0.005 |
Safety
| Outcome | P value |
|---|---|
| Institutional blood glucose readings within goal range (71-179 mg/dL)Reduction after; presumably an increase in hyperglycemia | P < 0.0001 |
Original publication
Reducing Inpatient Hypoglycemia: A Diversified Approach to a Complex Problem. Endocr Pract. Published 2 June 2025. doi:10.
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