Lipids & metabolic liver disease
Hypertriglyceridemic waist phenotype, hypertriglyceridemic waist-to-height ratio phenotype and abnormal glucose metabolism in adolescents
Main finding · Abnormal glucose metabolismResult — go to the resultOdds ratio 1.548Authors' conclusion
The study demonstrates that HWHtR phenotype was closely associated with an increased risk of abnormal glucose metabolism in adolescents. Adolescents with HWHtR phenotype had worsen insulin resistance and increased insulin secretion as a result of compensation.
Study context
- Population
- Adolescents aged 12–19 years in United States
- Participants
- 2,626 adolescents
- Exposure
- Hypertriglyceridemic waist (HW) and HWHtR phenotype vs without phenotype
- Outcome
- Abnormal glucose metabolism: FPG ≥ 5.6 mmol/L or OGTT 2-h plasma glucose ≥ 7.8 mmol/L or HbA1c ≥ 5.7% or previous diagnosis of diabetes
Methodological detailssecondary analysis
- Secondary analysis
Main finding
Abnormal glucose metabolism
Odds ratio
1.548
P = 0.010
By group
As reported in the abstract
- Overall prevalence of abnormal glucose metabolism
- 621 (23.6%)
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| HOMA-IR and β cell function indexHWHtR phenotype vs Without HWHtR phenotype · higher with HWHtR phenotype | P < 0.001 |
Original publication
Hypertriglyceridemic waist phenotype, hypertriglyceridemic waist-to-height ratio phenotype and abnormal glucose metabolism in adolescents. Diabetes Res Clin Pract. Published 15 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →