Lipids & metabolic liver disease
Burden of liver complications related to non‐alcoholic fatty liver disease in China from 2005 to 2019: Observations from the Global Burden of Disease Study, 2019
Authors' conclusion
The LC-NAFLD burden in China is substantial and has increased markedly over the past 15 years. Effective measures for low SDI regions and men are needed to address the rapidly increasing NAFLD burden.
Study context
- Population
- China, 2005–2019; liver complications related to NAFLD (LC-NAFLD)
- Primary endpoint
- Burden of LC-NAFLD (prevalence and DALYs)
- Follow-up
- 2005 to 2019
Methodological detailsJoinpoint regression, Gaussian process regression
- Joinpoint regression
- Gaussian process regression
Primary result
As reported in the abstract
LC-NAFLD burden in China · 2019
LC-NAFLD cases
293.42 million
95% UI 263.69–328.44
Prevalence rate per 1000 people
20.63
95% UI 23.09–18.54
Disability-adjusted life-year (DALYs)
591.03 thousand
95% UI 451.25–737.33
Further findings
Regional distribution · 2019
- North China had the highest prevalence but the lowest DALYs; Southwest China the lowest prevalence but the highest DALYs
Sex difference · 2019
- More common in men than women; male:female ratio
- 1.27
Change in NAFLD cases · 2005 to 2019
- Increase in prevalence of NAFLD cases (174.32 million in 2005 to 293.42 million in 2019), mainly due to age-specific prevalence rate increase
- 68.32%
Original publication
Burden of liver complications related to non‐alcoholic fatty liver disease in China from 2005 to 2019: Observations from the Global Burden of Disease Study, 2019. Diabetes Obes Metab. Published 7 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →