Obesity

Hypertension and hypercholesterolemia are predictive factors associated with type 2 diabetes persistence after metabolic surgery: A prospective study

Diabetes Res Clin PractPublished Prospective cohort study

Authors' conclusion

In a cohort of patients with obesity and T2DM, preoperative hypertension and hypercholesterolemia, together with a longer diabetes duration and higher HbA1c concentrations, were independent predictors of T2DM persistence after metabolic surgery.

Study context

Population
Patients with obesity and T2D undergoing metabolic surgery
Participants
98 patients
Exposure
Pre-surgery clinical and biochemical factors in T2D remission vs persistence after metabolic surgery
Outcome
T2D remission
Follow-up
1 year after metabolic surgery

Main finding

As reported in the abstract

1 year

Hypertension vs No hypertension: P < 0.001 · Hypercholesterolemia vs No hypercholesterolemia: P < 0.001 · Diabetes ≥5 years vs Diabetes <5 years: P < 0.001

Observational data: associations, not effects.

Further findings

Baseline characteristics of non-remission vs remission · before surgery

Patients without remission had longer diabetes duration, higher HbA1c, and more often used insulin, antihypertensive drugs and lipid-lowering therapies before surgery than those with remission

Original publication

Hypertension and hypercholesterolemia are predictive factors associated with type 2 diabetes persistence after metabolic surgery: A prospective study. Diabetes Res Clin Pract. Published 2 April 2023. doi:10.1016/j.diabres.2023.110650

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