Hypertension and hypercholesterolemia are predictive factors associated with type 2 diabetes persistence after metabolic surgery: A prospective study
Authors' conclusion
In a cohort of patients with obesity and T2DM, preoperative hypertension and hypercholesterolemia, together with a longer diabetes duration and higher HbA1c concentrations, were independent predictors of T2DM persistence after metabolic surgery.
Study context
- Population
- Patients with obesity and T2D undergoing metabolic surgery
- Participants
- 98 patients
- Exposure
- Pre-surgery clinical and biochemical factors in T2D remission vs persistence after metabolic surgery
- Outcome
- T2D remission
- Follow-up
- 1 year after metabolic surgery
Main finding
As reported in the abstract
1 year
Hypertension vs No hypertension: P < 0.001 · Hypercholesterolemia vs No hypercholesterolemia: P < 0.001 · Diabetes ≥5 years vs Diabetes <5 years: P < 0.001
Observational data: associations, not effects.
Further findings
Baseline characteristics of non-remission vs remission · before surgery
- Patients without remission had longer diabetes duration, higher HbA1c, and more often used insulin, antihypertensive drugs and lipid-lowering therapies before surgery than those with remission
Original publication
Hypertension and hypercholesterolemia are predictive factors associated with type 2 diabetes persistence after metabolic surgery: A prospective study. Diabetes Res Clin Pract. Published 2 April 2023. doi:10. 1016/ j. diabres. 2023. 110650
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