Hyperglycemia in Hospital: An Independent Marker of Infection, Acute Kidney Injury, and Stroke for Hospital Inpatients
Authors' conclusion
In hospital inpatients (HbA1c ≤12.0%), irrespective of diabetes status and prehospital glycemia, hyperglycemia increases the risk of in-hospital HAI, AKI, and stroke compared with those not experiencing hyperglycemia.
Study context
- Population
- Hospital inpatients with and without diabetes (HbA1c ≤12.0%), ≥2 capillary glucose values and LOS >24 hours, Royal Melbourne Hospital, Australia; October 2019-March 2020
- Participants
- 2,558 admissions
- Exposure
- Hyperglycemia in hospital vs no hyperglycemia
- Hyperglycemian = 1,147
- Outcome
- HAI, acute kidney injury (AKI), stroke, and mortality
- Follow-up
- In-hospital, up to day 14 of admission
Methodological detailspropensity-weighted, single-centre
- Propensity-weighted
- Single-centre
Main finding
As reported in the abstract
In-hospital HAI, AKI and stroke
Hyperglycemia vs No hyperglycemiaEstimate (95% CI)P value
HAI: 130 [11.3%] vs 100 [7.1%]
aOR (HAI) 1.03(1.01–1.05)
P = 0.003AKI: 120 [10.5%] vs 59 [4.2%]
aOR (AKI) 1.07(1.05–1.09)
P < 0.001Stroke: 10 [0.9%] vs 1 [0.1%]
aOR (stroke) 1.05(1.04–1.06)
P < 0.001Observational data: associations, not effects.
Original publication
Hyperglycemia in Hospital: An Independent Marker of Infection, Acute Kidney Injury, and Stroke for Hospital Inpatients. J Clin Endocrinol Metab. Published 27 January 2024. doi:10.
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