Diabetes technology

Human factor in the use of automated insulin delivery systems: Real-world effects in children with type 1 diabetes after 2 years of use (AID-A study)

Diabetes Res Clin PractPublished Real-world longitudinal cohort study

Authors' conclusion

AID system use is associated with clinically relevant improvements in glycaemic control and decrease in daily diabetes-related burden on affected children and their parents.

Study context

Population
Children with T1D using AID systems in a real-world setting
Participants
111 children
Exposure
Before vs after 1 and 2 years of AID use
Outcome
Glycaemic control
Follow-up
1 year

Main finding

As reported in the abstract

HbA1c decreased (from → to)

8.1 % (65 mmol/mol) to 7.7 % (61 mmol/mol)

TIR increased (from → to)

55 % to 64 %

TBR decreased (from → to)

2.6 % to 1.8 %

GMI improved

7.6 % vs. 7.3 %

Observational data: associations, not effects.

Further findings

Glycaemic control (stabilised) · 2 years

HbA1c
7.6 % [60 mmol/mol]
TIR
62 %
TBR
1.3 %
GMI
7.4 %

Daily life

Adolescents and parents reported improvements in daily life (sleep, stress, fear of hypoglycaemia)

Safety

BMI-SDS scores increased in the first year

Original publication

Human factor in the use of automated insulin delivery systems: Real-world effects in children with type 1 diabetes after 2 years of use (AID-A study). Diabetes Res Clin Pract. Published 9 September 2025. doi:10.1016/j.diabres.2025.112477

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