A Simple Meal Bolus Strategy is Effective in Adolescents and Young Adults with Type 1 Diabetes on Multiple Automated Insulin Delivery Systems
Primary result · TIR 70-180 mg/dLResult — go to the resultDifference −1.8% 95% CI lower limit −3.9Authors' conclusion
Precise CC may be an unnecessary burden for T1D adolescents using AID, and requiring it could impact success with or access to these systems.
Study context
- Population
- Adolescents and young adults aged 14–26 with T1D using automated insulin delivery (AID); mean 17.4 years, 51.6% female, T1D duration 8.3 years, baseline time in range (TIR) 64.1%crossover
- Participants
- 31 adolescents
- Comparison
- Simple meal boluses vs carbohydrate counting
- Primary endpoint
- TIR 70-180 mg/dL, noninferiority margin 5%
- Follow-up
- 4 weeks per period
Methodological detailsnoninferiority
- Noninferiority
Primary result
TIR 70-180 mg/dL
Difference
−1.8%
95% CI lower limit −3.9
P = 0.008 indicating noninferiority
By group
Simplevs CC
difference −1.8% (95% CI lower limit −3.9); P = 0.008 indicating noninferiority
As reported in the abstract
Further findings
% time >250 mg/dL · 4 weeks per period
- No difference in % time >250 mg/dL between periods (difference, P = 0.3)
- 1.2%
- Crossover
Preferred meal bolus method after study
- Preferred carbohydrate counting (CC)
- 31.3%
- Preferred simple boluses
- 40.6%
- Preferred prestudy method
- 28.1%
Safety
% time <70 mg/dL · 4 weeks per period
- No difference in % time <70 mg/dL between periods (difference, P = 0.9)
- −0.02%
- Crossover
Original publication
A Simple Meal Bolus Strategy is Effective in Adolescents and Young Adults with Type 1 Diabetes on Multiple Automated Insulin Delivery Systems. Diabetes Technol Ther. Published 15 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →