Automated Insulin Delivery Systems in Hospitals: A Systematic Review with Meta-Analysis
Pooled result · TIR, non-ICU settingResult — go to the resultIncrease in TIR 24.6 percentage points 95% CI 20.7–28.5Authors' conclusion
AID systems can be safely and effectively used in non-ICU hospital settings to improve glycemic outcomes.
Study context
- Population
- Inpatients in non-ICU (>80% T2D) and intensive care unit (ICU) (with and without preexisting diabetes) settings5 non-ICU randomized controlled trials (RCTs) (N = 300)
- Comparison
- Automated insulin delivery (AID) vs control in hospital inpatients
- Outcome
- TIR 5.6-10.0 mmol/L (100-180 mg/dL)
Methodological detailsPRISMA 2020, ICU and non-ICU settings analysed separately, Search of MEDLINE, Embase and CENTRAL on March 27, 2026; 4858 references screened
- PRISMA 2020
- ICU and non-ICU settings analysed separately
- Search of MEDLINE, Embase and CENTRAL on March 27, 2026; 4858 references screened
Pooled result
TIR, non-ICU setting
Increase in time in range (TIR)
24.6 percentage points
95% CI 20.7–28.5
AIDvs Control
increase in TIR 24.6 percentage points (95% CI 20.7–28.5)
As reported in the abstract
Further pooled results
Hyperglycemia, all settings
- AID associated with reduced hyperglycemia
Clinical outcomes
- Clinical outcomes were sparsely reported
Safety
Hypoglycemia, all settings
- No increase in hypoglycemia with AID
Original publication
Automated Insulin Delivery Systems in Hospitals: A Systematic Review with Meta-Analysis. Diabetes Technol Ther. Published 24 June 2026. doi:10.
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